Worldwide, lives are stressed and strained by COVID-19. Nowhere is that more evident than in the lives of students, staff and faculty members engaged in the transformed role of online learning. As higher education adapts to teaching and learning at a distance, the workload and the learning load of adopting a new delivery mode is taking a huge toll on the lives of those in higher education. This is an immense problem that is growing rapidly. While there are some students who are thriving through online learning, the toll of the virus, isolation, increased workloads and other associated effects are rising among many students, staff and faculty members. It must not be underestimated. Every institution must address these challenges that threaten the well-being of their constituents.