Leveraging Universal Design for Learning, or UDL, will help ensure effectiveness and a level of normalcy in an unexpected new learning reality. UDL comes from an educational framework first conceptualized in architecture with Universal Design – creating spaces that are accessible to all – and the challenges of special education, where learning and teaching based on the “average” student was not effective. A framework that considers wide differences in human behavior and teaches to every student is critical now more than ever. UDL provides a framework to reach every student through online teaching by utilizing neuroscience for learning and following the 3 main principles of engagement, representation, and action and expression.