In so very many ways, we in higher education have fallen behind business, industry, governments and society as a whole. We are offering programs and products that may have been relevant 50 or a hundred years ago but are not in touch with the society of the fourth industrial revolution. Imagine for a moment that we are creating a university anew in 2022. What would we change? What would we retain? How would it differ from what students, faculty and staff currently experience? Within some broad topical areas, here are starting points for the discussion.